Pathogenic variants of the nucleotide sequence in the SPATA16 gene in homozygous and compound heterozygous states have been described in patients with spermatogenesis disorder, type 6 (SPGF6), associated with oligoasthenoteratozoospermia, globozoospermia (OMIM 102530). The gene discussed is SPATA16; the disease is oligoasthenoteratozoospermia.