Therefore, the aim of this study was to construct a personalised model for predicting PPGR applicable to patients with T1D by collecting data on insulin dose, nutrient content of diet and additional clinical indicators from 13 patients with T1D in Kunming, Yunnan Province, in order to better guide the dietary plan as well as the dose of insulin intake in patients with T1D. The gene discussed is INS; the disease is type 1 diabetes mellitus.