Also, Shobeiri et al. [36] demonstrated that the M7 anti-IL-17A aptamer administration on the IMQ-induced psoriasis C57BL/6 mice dorsal skin ameliorated severity manifestations of skin psoriasis and reduced the IL-17A, IL-1b, and S100a9 mRNA expression levels[36]. The gene discussed is S100A9; the disease is psoriasis.