The study further evaluated the anti-cancer effects through the inhibition of NaV1.7 using PF-05089771 (Swain et al., 2017) in EC cells and showed an increase in EC cell apoptosis whereas the activation of NaV1.7 using veratridine (Zhang et al., 2018) reduced the late apoptosis (Liu et al., 2019). The gene discussed is SCN9A; the disease is cancer.