More recently, our group reported the expression of NaV1.5, NaV1.6 and NaV1.7 channels in two medullary thyroid cancer (MTC) cell lines: MZ-CRC-1 (metastatic) and TT (primary tumor) using quantitative RT-PCR and immunoblotting assays48. Here, SCN5A is linked to medullary thyroid gland carcinoma.