SCN9A and medullary thyroid gland carcinoma: In addition, NaV1.7 is found to be overexpressed in gastric cancer tissues and cell lines, BGC-823 and MKN-28 (Xia et al., 2016), in endometrial cancer cells and biopsies (Liu et al., 2019), in primary malignant pleural mesothelioma (MPM) cells obtained from patient specimens (Fulgenzi et al., 2006), in human neuroblastoma cell line, SH-SY5Y (Vetter et al., 2012), and in human medullary thyroid cancer tissues and cell lines, MZ-CRC-1 (highly metastatic) and TT (primary tumor) (Pukkanasut et al., 2023).