In 2010, the expression of NaV1.1 to NaV1.9 were investigated in the highly metastatic ovarian cancer cell lines, Caov-3, SKOV-3, and in a weakly metastatic ovarian cancer cell line, Anglne to correlate their expression to the rate of metastasis (Gao et al., 2010). This evidence concerns the gene SCN1A and ovarian cancer.