Enrichment analysis of concurrent Genes Involved in AD showed that the terms were mainly enriched in cytokine signaling in immune system, PI3K-Akt signaling pathway, mitochondrial matrix, inflammatory response, and positive regulation of superoxide anion generation (Figure 4C), whereas PD was related to histone modifying activity, regulation of muscle system process, focal adhesion, regulation of metal ion transport and negative regulation of striated muscle cell differentiation (Figure 4D). This evidence concerns the gene AKT1 and Alzheimer disease.