UBXN11 and hepatobiliary disorder: At the level of SOC, nervous system disorders (4,471, ROR 1.90, PRR 1.97, IC 0.69, EBGM 1.61) met the thresholds for ROR and IC criteria, while blood and lymphatic system disorders (2,594, ROR 4.08, PRR 4.26, IC 1.80, EBGM 3.49) and hepatobiliary disorders (1,321, ROR 3.63, PRR 3.85, IC 1.75, EBGM 3.37) reached the thresholds for all four methodological approaches (Supplementary Table S4).