TLR3 and tetanus: Briefly, his T-cell subset counts were normal with reduced ratios (CD3 count 2107/cmm with 29 % ratio; CD4 count 1018/cmm with 14 % ratio), B-lymphocyte count and ratio were significantly elevated (>863/cmm with 63 % ratio), lacked response to tetanus and pneumococcal vaccines, and no clinically significant variants of TLR3 gene were identified.