Numerous crucial pathways and mechanisms, including those involving sex hormones, extracellular matrix (ECM), Wnt/β-catenin, TGF-β, growth factors, epigenetic and epitranscriptomic regulation, YAP/TAZ, Rho/ROCK, and DNA damage repair pathways, play a role in the development of uterine fibroids [18]. Here, RHO is linked to uterine corpus leiomyoma.