CD4 and neoplasm: In this study, tumor immunological profiling following bacterial depletion revealed an increase in anti-tumor immune lymphocytic cells (CD3+CD4+IFNγ+, CD3+CD8+IFNγ+, and CD3+IFNγ+), while a decrease in pro-tumorigenic IL17a (IL17a + CD3 +) and IL10(IL10 + CD4 + CD3 +).