These terms included cell-cell signaling, cell adhesion, transcription export complex, cell-adhesion molecule binding, and platelet-derived growth factor receptor binding etc. The KEGG pathway enrichment analysis results for differentially expressed lncRNAs target genes between the RA-HW and Normal groups demonstrated primary enrichment of upregulated lncRNAs in pathways, such as the PI3K-Akt signaling pathway (Figure 1D). This evidence concerns the gene AKT1 and rheumatoid arthritis.