AKT1 and rheumatoid arthritis: These terms included cell division, cell cycle process, cell-cell junction, transcription factor binding, and sequence-specific DNA-binding transcription factor activity etc. The KEGG pathway enrichment analysis results for differentially expressed lncRNA target genes between the RA-LW and Normal groups demonstrated primary enrichment of upregulated lncRNAs in pathways, such as the PI3K-Akt and AMPK signaling pathways (Figure 3D).