Autophagy has also been reported to be compromised in neurodegenerative diseases including Huntington disease (HD), an autosomal dominant monogenic neurodegenerative disease caused by the expansion of CAG repeats in the first exon of huntingtin gene (HTT) that produce aggregation‐prone mutant huntingtin protein (mHTT) (Giovedì et al., 2020; Menzies et al., 2015). The gene discussed is HTT; the disease is neurodegenerative disease.