Consistently, these combinations were effective in decreasing cells positive for Ki67 staining and increasing cells positive for cPARP staining in both PC‐9/AR and HCC827/AR tumor tissues while either agent in the combination alone had minimal or no effect (Figure S12B, Supporting Information), indicating enhanced inhibition of cell proliferation with induction of apoptosis in vivo. The gene discussed is MKI67; the disease is neoplasm.