Wang et al. [9]summarized the data of Chinese HS patients from 2000 to 2020, and the proportions of ANK1, SPTB, SLC4A1, and SPTA1 mutations were 46%, 42%, 11%, and 1%, respectively, which is similar to the research data from Korea [10]. This evidence concerns the gene SPTB and histiocytic sarcoma.