In a rat model of CCL4-induced liver fibrosis, miR-23a induces liver fibrosis through the PTEN/PI3K/Akt/mTOR/snail signaling pathway, while lncRNA-GAS5 acts as a ceRNA to decrease miR-23a expression and suppressing liver fibrosis [38]. This evidence concerns the gene AKT1 and Hepatic fibrosis.