TSPO and migraine disorder: A recent PET-MRI study confirmed this finding which was conducted with patients that had at least 1 migraine attack with aura and healthy controls, used a (11C)PBR28 radio ligand that binds to a glial marker 18 kDa translocator protein which increases during neuroinflammation, showed an increase in inflammatory signal in cortical and subcortical structures bilaterally in migraine patients and the signal intensity was found to correlate with the number of migraine attacks [45].