Although the exact mechanism of this association is not known, pregnancies complicated with FHD have been found to express lower levels of angiogenic factors like the Placental Growth Factor (PlGF) [15] and higher levels of anti-angiogenic factors such as soluble fms-like tyrosine kinase 1 (sFl-t1) [24]. Here, PGF is linked to hypoalphalipoproteinemia, primary, 1.