First, positive correlations were observed between % JAK2 V617F and the white blood cells (WBC) counts (P < 0.05), as well as the endogenous serum globulin beta-2 microglobulin (β2-MG) levels (P < 0.001) across all three types of MPN patients. The gene discussed is JAK2; the disease is myeloproliferative disorder.