In this study, we examined three cardiomyogenic differentiation inducers’ – Decitabine, Angiotensin II and TGF-β1, effect on endometrium origin stromal cells, including menstrual (MenSCs), endometrium (EndSCs) and endometriosis (EmsSCs) stromal cells, and evaluated their ability to demonstrate cardiac-like phenotype as well as investigated the regulation processes that directed the cells to undergo these changes. Here, TGFB1 is linked to endometriosis.