Likewise, more Iba1+/CD44+/OPN+ cells were identified in the affected WM (183.05 ± 133.3/mm2) as compared to the WM contralateral to infarction (2.4 ± 3.02/mm2) and the comparison to Sham WM (3.1 ± 2.6/mm2) approached statistical significance. The gene discussed is SPP1; the disease is infarction.