To investigate whether overexpression of MIR155HG enhanced the therapeutic effect of PD-L1 mAb treatment, we utilized anti-human PD-L1 mAb to treat PBMC-transferred immunodeficient NCG mice inoculated subcutaneous xenograft with A549-vector/MIR155HG or A549-sh-NC/sh-MIR155HG lung cancer cells (Fig. 7F). Here, CD274 is linked to lung cancer.