Confocal laser scanning microscopy (CLSM) images revealed that both the NPαPDL1+α4-1BB- and Tri-NAb-treated groups exhibited enhanced interactions between CD8+ T (green) and MC38 tumor cells (red), while NPαPDL1+αNKG2A and Tri-NAb effectively promoted interactions between NK (blue) cells and tumor cells. Here, CD8A is linked to neoplasm.