FGFR4 and neoplasm: Nevertheless, both the CD276.8HTM.BBz single CAR and FGFR4.28HTM.28z-CD276.8HTM.BBz BiCisCAR T-cells controlled tumor and significantly increased survival, with the BiCisCAR demonstrating a swifter tumor clearance (Fig. 4H, I; Supplementary Fig. 8A).