TNF and neoplasm: Aberrant inflammation is a significant trait inGBM, which notonly endows tumor cells with an immune evasion ability but also exacerbatestumor proliferation, invasion, and relapse.45,46 In this study, DHA liposomes were able to successfully mitigatethe inflammatory profile in stimulated macrophages (Figure 4) and GBM cells (Figure 5), by reducing IL-6, IL-1β, and TNFα geneexpression.