ITGAM and systemic lupus erythematosus: The percentages of splenic CD11b+Ly6G+ neutrophils and CD11b+F4/80+Gr1lo/int macrophages were increased in both female and male SLE-prone recipients reconstituted with Cybb-KO BM (Supplemental Table 1; supplemental material available online with this article; https://doi.org/10.1172/jci.insight.178563DS1), as also observed in globally Cybb-deficient MRL.Faslpr mice (20).