GPT and cognition: Adjusting for all covariates, the highest ALT quartile consistently demonstrated a lower likelihood of impaired cognitive function compared to the lowest quartile, with OR (95%CI) values of 0.55 (0.37–0.82) for global cognitive performance (Table 2), 0.53 (0.37–0.76) for CERAD (Table 3), and 0.53 (0.34–0.80) for DSST (Table 3) (P for trend < 0.01).