The results of the fully adjusted model indicated that ALP was negatively associated with the animal fluency test (AFT) score (OR = 1.48, 95% CI: 1.11–1.98), whereas ALT demonstrated a positive association with the consortium to establish a registry for Alzheimer’s disease (CERAD) test score (OR = 0.72, 95% CI: 0.53–0.97). This evidence concerns the gene GPT and Alzheimer disease.