GPT and Cognitive impairment: In the fully adjusted model, AST/ALT levels were significantly associated with an increased risk of cognitive impairment, with an OR (95% CI) 2.39 (1.53–3.73) for global cognitive performance (Table 2), 2.61 (1.77–3.84) for CERAD (Table 3), and 2.51 (1.57–4.02) for DSST (Table 3).