To further validate the presence of FAP+ fibroblasts across both CD and UC in colon, we analyzed transmural samples from healthy CRC colon (unaffected), healthy CD colon (non-inflamed), inflamed/stenotic CD colon (granulating ulcer and thickened bowel wall), and UC colon (inflamed) using flow cytometry (Supplemental Figure 2J). Here, FAP is linked to colorectal carcinoma.