Among patients included in the current analysis, mean age was 69 ± 12 years, 73% were female, median body mass index was 22 ± 4 kg/m2, 43% had hypertension, 14% had diabetes mellitus, 52% were diagnosed with breast cancer, 77% were treated with anthracycline drug, mean systolic blood pressure (BP) was 131 ± 22 mmHg, and median b-type natriuretic peptide (BNP) was 20 (10 to 78) pg/ml. This evidence concerns the gene NPPB and breast cancer.