LGALS3 and acute kidney injury: Moreover, scRNAseq data from human biopsies of control vs. AKI patients show significantly upregulated LGALS3 mRNA in proximal tubules, thick ascending limb, distal convoluted tubules, connecting tubules, collecting duct principal cells, and endothelial cells (https://shiny.mdc-berlin.de/humAKI/) [20].