In addition to removing alkyl adducts from DNA lesions, MGMT is highly expressed in pancreatic cancer,[18] and the suppression of MGMT activity by the pharmaceutical compound O6‐benzylguanine (O6‐BG) decreases cancer cell proliferation and induces cell apoptosis;[19] these results indicate that MGMT can also play a biologically important role in tumor development. This evidence concerns the gene MGMT and familial pancreatic carcinoma.