The proportional areas of steatosis, CD45-, Iba1-, and SMA-positive staining decreased significantly by ≈75% (P < 0.0001), ≈65% (P < 0.0001), ≈65% (P < 0.001) and ≈45% (P = 0.0004), respectively (Fig. 6, A-D). Here, SMN1 is linked to steatosis.