SLC7A11, a member of the amino acid transporter SLC7 family, is induced by IL‐1β to upregulate PD‐L1 and CSF1 through αKG/HIF1α axis, leading to infiltration of tumor‐associated macrophages and myeloid‐derived suppressor cells and promoting metastasis of HCC [41]. This evidence concerns the gene HIF1A and hepatocellular carcinoma.