Finally, miR‐455‐3p levels were comparable in the two populations of EVs (healthy vs RA donor) (Figure 6I) and, similarly to healthy donor EVs, RA EVs could revert the up‐regulation of COL10A1 gene product in chondrocytes following IL‐1β stimulation (Figure 6J). The gene discussed is IL1B; the disease is rheumatoid arthritis.