IGF2BP2 and neoplasm: Studies have shown that IGF2BP2 is overexpressed in many cancers, correlates with progression, and promotes cancer cell proliferation and migration (reviewed in Cao et al., 2018), while we and others have reported that circHIPK3 is downregulated in BC (Okholm et al., 2017) and possess tumor suppressor functions (Teng et al., 2019).