CCNB1 and neoplasm: In the CCNB1-prostate set, patients with high CCNB1 had significantly shorter TTR compared to those with high CCNB1 tumours for both manual scores (HR = 2.30, 95 % CI 1.45–3.65), and DL scores (HR = 2.10, 95 % CI 1.30–3.38), (Fig. 4a (G and H), Table 2).