We previously developed a software called the interactive Cross-Phenotype Analysis of GWAS database (iCPAGdb) to study pleiotropy by comprehensively identifying shared association signals between user-uploaded GWAS and all publicly cataloged GWAS summary statistics.10,11 Using the first COVID-19 GWAS published by Ellinghaus et al.12 and the highest-powered IPF GWAS at the time,13 we identified a shared signal in DPP9, rs12610495, associated at a suggestive threshold with severe COVID-19 (p-value = 5.20 × 10−6)12 and at genome-wide significance with IPF (p = 2.92 × 10−12)13. The gene discussed is DPP9; the disease is idiopathic pulmonary fibrosis.