Thus, we evaluated the cytokine production ability of BM monocytes from naïve and from LPS-treated mice (Figure 3H, Supplementary Figure 2E) and found that BM monocytes from LPS-treated mice showed significantly lower production of TNF-α, a representative cytokine involved in sepsis induction, and CXCL1 (Figure 3H). The gene discussed is TNF; the disease is Sepsis.