The pathological manifestations of AD include the imbalances in Th1, Th2 and Treg cell immunity and the increased Th2 cytokines IL‐4 and IL‐13, which may ultimately alter Th1‐ and Th2‐mediated immune responses and IgE‐mediated hypersensitivity.2 The gene discussed is IL4; the disease is Alzheimer disease.