Relative to normal paracancerous tissue samples, both OSCC and OLP tissues exhibited significant reductions in the levels of Sox11 promoter methylation, with respective methylation rates in average, OLP, and OSCC tissues of 72.59 ± 5.69, 57.70 ± 6.89, and 36.50 ± 9.12, respectively (Figure 2A,B). This evidence concerns the gene SOX11 and oral lichen planus.