As depicted in Fig. 4, anemia [men: hazard ratio (HR) = 1.96, 95% confidence interval (CI) = 1.02 to 3.73, P = 0.043; women: HR = 2.63, 95% CI = 1.10 to 4.99, P = 0.035], insulin use [men: HR = 1.81, 95% CI 1.01 to 3.23, 0.045; women: HR = 2.09, 95% CI 1.01 to 4.14, P = 0.048], LGE presence [men: HR = 2.34, 95% CI 1.06 to 4.17, P = 0.036; women: HR = 2.56, 95% CI 1.05 to 4.53, P = 0.041] and GLS [men: HR = 1.19, 95% CI 1.01 to 1.40, P = 0.033; women: HR = 1.39, 95% CI 1.04 to 1.84, P = 0.026] were the common independent predictors of adverse outcomes for both men and women. Here, INS is linked to anemia.