Univariate Cox regression revealed that history of stroke, creatinine (Cr), left ventricular ejection fraction(LVEF), TG, HDL, TC/HDL, ApoB, ApoA1/ApoB, Fg, pulmonary artery pressure (PAP), high GS group, TVD, and PCSK6 rs1531817 genotypes were associated with the occurrence of MACEs (Table S4). The gene discussed is APOA1; the disease is Stroke.