However, the presence of conflicting results concerning the association between the CYP1A2-163 C/A and CYP1A2-3860 G/A polymorphisms and the risk of bladder carcinoma can be attributed, in part, to limited sample sizes and the modest impact of genetic variations on the development of bladder cancer [16]. The gene discussed is CYP1A2; the disease is urinary bladder carcinoma.