In another study, using mice liver tissue infected by virulent and avirulent strains of T. gondii, El-Sayad et al. [30] detected significant overexpression of miRNA-155 with a significant reduction of butyrylcholinesterase in all infected cells, but were maximal in cells infected by virulent strains especially at 7-d after infection and concluded that miRNA-155 and butyrylcholinesterase play a role in regulating host-parasite interaction in toxoplasmosis. This evidence concerns the gene BCHE and toxoplasmosis.