Through examination of the RNA-seq matrix as well as clinical information pertaining to gliomas, we discovered that there were statistically significant differences in UNC5A expression with age (p = 0.025), grade (p < 0.001), chemo status (p = 0.004), 1p19q codeletion status (p < 0.001), IDH mutation (p < 0.001), as well as histology (p < 0.001), while it was not significant in gender, radio status (p = 0.405), or PRS type (p = 0.998) (Fig. 4). This evidence concerns the gene UNC5A and central nervous system cancer.