Among those proteins significant in only one disease group, MCI included increased ribosome proteins (RPL28, RPL35A, RPS10), and AD included decreased 14-3-3 family proteins (YWHAB, YWHAE, YWHAG, YWHAH, YWHAZ; as well as YWHAQ in both AD and MCI). This evidence concerns the gene YWHAE and Alzheimer disease.