Treatments that target ATXN2 may help reduce the symptoms of PD or delay disease progression [47].ATXN2 plays multiple roles in neurological function and neurodegenerative diseases, including directly affecting neurological function through specific molecular and cellular pathways [52].Therefore, therapeutic strategies that target the complex functions of ATXN2 may be useful in the treatment of a wide range of neurodegenerative diseases. Here, ATXN2 is linked to neurodegenerative disease.