These proteins included TNF receptor superfamily member 17 (TNFRSF17 or B cell maturation antigen)—a specific predictor for MM—and TNFRSF13B—a strong predictor of monoclonal gammopathy of undetermined significance (MGUS), a condition that precedes the development of MM (at a rate of ~1 in 100 MGUS cases developing MM per year18). This evidence concerns the gene TNFRSF17 and monoclonal gammopathy.