We then profiled the proteomes of four types of melanoma cells with different PRKDC expression patterns, namely, Vector-OE-high (OE-Control-HMCB), PRKDC-OE-HMCB, Scramble-shRNA-HMCB (sh-Control-HMCB), and PRKDC-KD-HMCB. Here, PRKDC is linked to melanoma.