There were no genome-wide significant associations in the multiancestry meta-analysis for subsequent AIS or MACE events (Figures S1 and S2), but we did observe 2 genome-wide significant (P<5×10−8) genetic variants in specific ancestry analyses: rs76472767 near gene RNF220 on chromosome 1 in the African ancestry GWAS for subsequent MACE (Slope-Hunter corrected P=3.69×10−8) and rs13294166 near gene LINC01492 on chromosome 9 in the African ancestry GWAS for subsequent AIS (uncorrected P=3.77×10−8; Figure 2; Table S2; Figure S3). This evidence concerns the gene RNF220 and androgen insensitivity syndrome.