Out of 52 athletes, five were excluded from this analysis: four were positive for AD based on plasma p-tau181 values of 13.18 pg/ml (Simoa pTau-181 V1 Kit), 7.4 pg/ml, 2.8 pg/ml, and 2.5 pg/ml (Simoa pTau-181 V2 Kit), and one athlete had tau-PET pattern of retention suggestive of AD and total grey matter SUVR of 2.73. This evidence concerns the gene MAPT and Alzheimer disease.