To determine whether the regulatory role of myeloid-specific α9 in early atherosclerosis was model-dependent (Apoe−/− background) or not, we generated an additional model in which irradiated Ldlr−/− mice were reconstituted with the BM cells from either α9Mye-KO (α9fl/flLysMcre+/−) or α9WT (α9fl/flLysMcre−/−) mice. This evidence concerns the gene LDLR and atherosclerosis.